Hot Issues in Dermatologic Therapy. Part 5

Dermatologists should be aware of thalidomide’s potential difference
as a therapeutic broker, and middleman a outlet involved with the TONE
promulgation if a case with one of the diseases noted above may be a
someone for thalidomide.

Isotretinoin (Accutane) has been FDA-approved since
1982 for the handling of severe, recalcitrant nodular acne (Table 2).
Stephen Wolverton, MD, from Robert Indiana Establishment in
Indianapolis, Robert Indiana, reviewed the regulatory liberal arts of Accutane,
with a sharpness on pregnancy prevention and psychiatric concerns with
the drug.
An FDA advisory administrative unit coming together in September 2000
suggested that a pregnancy registry would be appropriate but a
psychiatry registry would not.

70,000 prescriptions/year in 1980s200,000 prescriptions/year in 20003/1000 pregnancy rate among women on Accutane (elective morpheme in 67%)5/1000 pregnancy rate among women on oral contraceptives (during point in time year of typical use).

The
Slone Epidemiology Unit of the Boston Educational institution Period of
Body Wellbeing is disposal a military man registry of individual Accutane users to determine whether women taking the teratogenic drug take appropriate footstep to avoid pregnancy.
Results indicate that the norm age of patients pregnant on Accutane was 26 assemblage, and 10% were pregnant at line.
Further, 43% of users did not wait until day 2-3 of menses to tiro Accutane therapy.

This is a part of article Hot Issues in Dermatologic Therapy. Part 5 Taken from "Generic Isotretinoin Accutane" Information Blog