A Review of Systemic Retinoid Therapy for Acne. Part 2

Initially with the debut of isotretinoin, only patients with severe
nodular cystic acne or severe inflammatory acne, who were not
responding to conventional therapy were given the drug.
Now, with more than 20 year of management occurrence, expanded
guidelines for its use include:

Moderate acne relapse (<50% improvement) after a 1 adequately-dosed facility of antibiotics

or hormonal therapy of 4 months

Significant psychosocial harm

Marked concomitant seborrhea

Gram photographic film folliculitis

Scarring or persistent dyschromia

Not
only deep nodular, but also superficial inflammatory acne can resultant
role in scarring.
Because scarring is frequently missed during questioning, proper price
of scarring is paramount and was well described in a recent issue.

Isotretinoin
is also of public presentation for patients with persistent brute acne
who have suffered for many life, or whose acne flares when adequate
conventional therapy has been discontinued.
Acne persisting into the 6th and 7th decades, termed “pensioners” acne”
has been treated with low dose (0.25mg/kg/day) or intermittent 1 week
in every 4 schedules.

This is a part of article A Review of Systemic Retinoid Therapy for Acne. Part 2 Taken from "Generic Isotretinoin Accutane" Information Blog